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Hirudin Fragment 54-65 non-sulfated_Molecular_structure_CAS_113274-56-9)
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Hirudin Fragment 54-65 non-sulfated

Catalog No. H6769 Name Sigma Aldrich
CAS Number 113274-56-9 Website http://www.sigmaaldrich.com
M. F. C66H93N13O25 Telephone 1-800-521-8956
M. W. 1468.51672 Fax
Purity ≥97% (HPLC) Email
Storage Chembase ID: 153347

SYNONYMS

IUPAC name
4-{2-[2-(2-aminoacetamido)-3-carboxypropanamido]-3-phenylpropanamido}-4-{[1-({1-[2-({1-[(1-{[1-({1-[(3-carbamoyl-1-carboxypropyl)carbamoyl]-3-methylbutyl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}-3-carboxypropyl)carbamoyl]-3-carboxypropyl}carbamoyl)pyrrolidin-1-yl]-3-methyl-1-oxopentan-2-yl}carbamoyl)-3-carboxypropyl]carbamoyl}butanoic acid
IUPAC Traditional name
4-{2-[2-(2-aminoacetamido)-3-carboxypropanamido]-3-phenylpropanamido}-4-{[1-({1-[2-({1-[(1-{[1-({1-[(3-carbamoyl-1-carboxypropyl)carbamoyl]-3-methylbutyl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}-3-carboxypropyl)carbamoyl]-3-carboxypropyl}carbamoyl)pyrrolidin-1-yl]-3-methyl-1-oxopentan-2-yl}carbamoyl)-3-carboxypropyl]carbamoyl}butanoic acid

DATABASE IDS

MDL Number MFCD00076563
PubChem SID 24895764
CAS Number 113274-56-9

PROPERTIES

Empirical Formula (Hill Notation) C66H93N13O25
Purity ≥97% (HPLC)
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Amino Acid Sequence
Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln
Biochem/physiol Actions
Hirudin fragment that binds to the regulatory exosite I (proexosite I) on prothrombin with lower affinity than the sulfated peptide. It inhibits the activation of prothrombin by factor Xa in the presence of factor Va.
Description (简体中文)
Amino Acid Sequence
Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln
Biochem/physiol Actions
Hirudin fragment that binds to the regulatory exosite I (proexosite I) on prothrombin with lower affinity than the sulfated peptide. It inhibits the activation of prothrombin by factor Xa in the presence of factor Va.

REFERENCES