4-Hydroxy-TEMPO

• Catalog No.: H8258
• CAS Number: 2226-96-2
• M. F.: C9H18NO2
• M. W.: 172.24472

SYNONYMS

• Title: 哌啶醇氧化物
• IUPAC name: ol
• IUPAC Traditional name: tyrosine(.)
• Synonyms: Tempol; 4-羟基-2,2,6,6-四甲基哌啶-1-氧自由基; 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl

DATABASE IDS

• EC Number: 218-760-9
• Beilstein Number: 1422990
• CAS Number: 2226-96-2
• MDL Number: MFCD00006478

PROPERTIES

• Empirical Formula (Hill Notation): C9H18NO2
• Melting Point: 69-71 °C(lit.)
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22-36/37/38
• RTECS: TN8991000
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 1

DETAILS

Description (English)

Application
Spin label reagent used in the chatacterization of antagonist and agonist binding sites of NK1 receptor. Also used to measure reactive oxygen generation in heart muscle by electron spin resonance spectroscopy. Cells that overexpress CYP2E1 can be protected from arachidonic acid toxicity damage by TEMPOL.

Description (简体中文)

Application
自旋标记试剂，用于鉴定 NK1 受体的拮抗剂和激动剂结合位点。也可用于电子自旋共振光谱法测定心肌中活性氧的生成。TEMPOL 可保护过量表达 CYP2E1 的细胞免受花生四烯酸的毒性损伤。