T-2 Toxin

• Catalog No.: T4887
• CAS Number: 21259-20-1
• M. F.: C24H34O9
• M. W.: 466.52136
• Purity: ≥98% (HPLC)

SYNONYMS

• Title: T-2 毒素
• IUPAC name: (1'S,2S,2'R,4'S,7'R,9'R,10'R,11'S)-11'-(acetyloxy)-2'-[(acetyloxy)methyl]-10'-hydroxy-1',5'-dimethyl-8'-oxaspiro[oxirane-2,12'-tricyclo[7.2.1.0^2,^7]dodecan]-5'-en-4'-yl 3-methylbutanoate
• IUPAC Traditional name: T-2 mycotoxin
• Synonyms: 4β,15-二乙酰氧基-3α-羟基-8α-(3-甲基丁酰氧)-12,13-环氧单端孢霉-9-烯; 4β,15-Diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene; 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate; 12,13-环氧单端孢霉-9-烯-3,4,8,15-四醇-4,15-二醋酸酯-8-异戊酸酯

DATABASE IDS

• Beilstein Number: 3575695
• EC Number: 244-297-7
• MDL Number: MFCD00871255
• CAS Number: 21259-20-1
• PubChem SID: 24900234

PROPERTIES

• Biological Source: from Fusarium sp.
• Empirical Formula (Hill Notation): C24H34O9
• Purity: ≥98% (HPLC)
• Apperance: white powder
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H310-H315-H330
• European Hazard Symbols: Highly toxic (T+)
• GHS Precautionary statements: P260-P264-P280-P284-P302 + P350-P310
• RID/ADR: UN 3462 6.1/PG 1
• Risk Statements: 26/27/28-38
• RTECS: YD0100000
• Safety Statements: 22-28-36/37/39-45
• Storage Temperature: -20°C
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• Hazard Class: 6.1
• UN Number: 3462
• Packing Group: 1
• German water hazard class: 3

DETAILS

Description (English)

Quality
Chromatographically purified
Biochem/physiol Actions
The trichothecenes, such as T2 Toxin, are mycotoxins produced by fungi of the genus Fusarium. They are commonly present in foods and feed of cereal origin. T-2 toxin induces DNA damage and cell death on prolonged administration. These effects can be partially blocked by antioxidants, such as glutathione, coenzyme Q10, or α-tocopherol. Increases blood-brain barrier permeability and inhibits monoamine oxidase activity in brain.

Description (简体中文)

Quality
Chromatographically purified
Biochem/physiol Actions
The trichothecenes, such as T2 Toxin, are mycotoxins produced by fungi of the genus Fusarium. They are commonly present in foods and feed of cereal origin. T-2 toxin induces DNA damage and cell death on prolonged administration. These effects can be partially blocked by antioxidants, such as glutathione, coenzyme Q10, or α-tocopherol. Increases blood-brain barrier permeability and inhibits monoamine oxidase activity in brain.