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GPR35 Agonist, Compound 10_Molecular_structure_CAS_123021-85-2)
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GPR35 Agonist, Compound 10

Catalog No. SML0174 Name Sigma Aldrich
CAS Number 123021-85-2 Website http://www.sigmaaldrich.com
M. F. C12H9NO5S Telephone 1-800-521-8956
M. W. 279.26856 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 153300

SYNONYMS

IUPAC name
2-{4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenoxy}acetic acid
IUPAC Traditional name
4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenoxyacetic acid
Synonyms
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid

DATABASE IDS

CAS Number 123021-85-2

PROPERTIES

Empirical Formula (Hill Notation) C12H9NO5S
Purity ≥98% (HPLC)
Apperance white to tan powder
Solubility DMSO: ≥5 mg/mL at ~60 °C
MSDS Link Download
Storage Temperature 2-8°C

DETAILS

Description (简体中文)
Biochem/physiol Actions
GPR35 agonist Compound 10 is a GPR35 agonist the binds with higher affinity than other known agonists, such as kynurenic acid and zaprinast. Compound 10 was more potent than zaniprast (pEC50 = 5.3 vs 4.18) for recombinantly expressed human GPR35, and unlike zaprinast, is equipotent for human and rat GPR35

REFERENCES