Montelukast sodium hydrate

• Catalog No.: SML0101
• M. F.: C35H37ClNNaO4S
• M. W.: 626.18035
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: sodium 2-[1-({[(1R)-1-{3-[2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetate hydrate
• IUPAC Traditional name: sodium 2-[1-({[(1R)-1-{3-[2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetate hydrate
• Synonyms: 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt hydrate

DATABASE IDS

• MDL Number: MFCD20527317

PROPERTIES

• Empirical Formula (Hill Notation): C35H35ClNO3S·Na · xH2O
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Optical Rotation: [α]/D +90 to +106° in methanol (c=1)
• Solubility: DMSO: ≥8 mg/mL at 60 °C
• Storage Condition: desiccated
• Storage Temperature: 2-8°C

DETAILS

Description (简体中文)

Biochem/physiol Actions
Montelukast sodium hydrate is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. It is a subtype specific CysLT1 receptor antagonist.