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Drospirenone

Catalog No. SML0147 Name Sigma Aldrich
CAS Number 67392-87-4 Website http://www.sigmaaldrich.com
M. F. C24H30O3 Telephone 1-800-521-8956
M. W. 366.4932 Fax
Purity ≥98% (HPLC) Email
Storage desiccated Chembase ID: 1206

SYNONYMS

IUPAC name
(1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.02,4.05,10.014,19.016,18]nonadecane-15,2'-oxolan]-5-ene-5',7-dione
IUPAC Traditional name
yasmin
Synonyms
6β,7β,15β,16β -Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone
Dihydrospirorenone

DATABASE IDS

MDL Number MFCD00867350
CAS Number 67392-87-4

PROPERTIES

Empirical Formula (Hill Notation) C24H30O3
Purity ≥98% (HPLC)
Apperance white to tan powder
Optical Rotation [α]/D -180 to -195°, c = 1 in methanol
Solubility DMSO: ≥15
MSDS Link Download
Storage Condition desiccated
Storage Temperature 2-8°C

DETAILS

Description (简体中文)
Biochem/physiol Actions
Drospirenone is a fourth-generation progestin that has antimineralocorticoid, and antiandrogenic activity in addition to potent progestogenic activity. In two recent studies drospirenone appeared to double the risk of venous thromboembolism compared to levonorgestrel, although other studies found little added risk.

REFERENCES