Home > Compound List > Product Information
R18 trifluoroacetate_Molecular_structure_CAS_211364-78-2(freebase))
Click picture or here to close

R18 trifluoroacetate

Catalog No. SML0108 Name Sigma Aldrich
CAS Number 211364-78-2(freebase) Website http://www.sigmaaldrich.com
M. F. C103H158F3N27O31S3 Telephone 1-800-521-8956
M. W. 2423.7091296 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 153269

SYNONYMS

IUPAC name
(2S)-1-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-5-carbamimidamido-2-{[(2S)-1-[(2S)-2-[(2R)-2-[(2S)-3-(1H-imidazol-4-yl)-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]-3-sulfanylpropanamido]-3-methylbutanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-carboxypropanamido]-4-methylpentanamido]-3-hydroxypropanamido]-3-(1H-indol-3-yl)propanamido]-4-methylpentanamido]-3-carboxypropanamido]-4-methylpentanamido]-4-carboxybutanamido]propanamido]-3-carbamoylpropanamido]-4-(methylsulfanyl)butanamido]-3-sulfanylpropanamido]-4-methylpentanoyl]pyrrolidine-2-carboxylic acid; trifluoroacetic acid
IUPAC Traditional name
(2S)-1-[(2S)-2-[(2R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-5-carbamimidamido-2-{[(2S)-1-[(2S)-2-[(2R)-2-[(2S)-3-(1H-imidazol-4-yl)-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]-3-sulfanylpropanamido]-3-methylbutanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-carboxypropanamido]-4-methylpentanamido]-3-hydroxypropanamido]-3-(1H-indol-3-yl)propanamido]-4-methylpentanamido]-3-carboxypropanamido]-4-methylpentanamido]-4-carboxybutanamido]propanamido]-3-carbamoylpropanamido]-4-(methylsulfanyl)butanamido]-3-sulfanylpropanamido]-4-methylpentanoyl]pyrrolidine-2-carboxylic acid; trifluoroacetic acid
Synonyms
L-Prolyl-L-histidyl-L-cysteinyl-L-valyl-L-prolyl-L-arginyl-L-a-aspartyl-L-leucyl-L-seryl-L-tryptophyl-L-leucyl-L-a-aspartyl-L-leucyl-L-a-glutamyl-L-alanyl-L-asparaginyl-L-methionyl-L-cysteinyl-L-leucyl-L-proline trifluoroacetate
PHCVPRDLSWLDLEANMCLP trifluoroacetate
Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro trifluoroacetate

DATABASE IDS

MDL Number MFCD20527319
CAS Number 211364-78-2(freebase)

PROPERTIES

Empirical Formula (Hill Notation) C101H157N27O29S3
Purity ≥98% (HPLC)
Shipped in wet ice
Apperance white to off-white powder
MSDS Link Download
Storage Temperature -20°C

DETAILS

Description (简体中文)
Biochem/physiol Actions
R18 is a competitive inhibitor of the 14-3-3 scaffolding proteins. It binds to the general binding groove of 14-3-3. R18 blocks 14-3-3 interaction with most or all of its client proteins.

REFERENCES