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OSU6162 hydrochloride_Molecular_structure_CAS_156907-84-5)
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OSU6162 hydrochloride

Catalog No. PZ0177 Name Sigma Aldrich
CAS Number 156907-84-5 Website http://www.sigmaaldrich.com
M. F. C15H24ClNO2S Telephone 1-800-521-8956
M. W. 317.87456 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 153267

SYNONYMS

IUPAC name
(3S)-3-(3-methanesulfonylphenyl)-1-propylpiperidine hydrochloride
IUPAC Traditional name
(3S)-3-(3-methanesulfonylphenyl)-1-propylpiperidine hydrochloride
Synonyms
PNU-96391; PNU-0096391; OSU-6162; (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine hydrochloride; (S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride

DATABASE IDS

MDL Number MFCD09753276
CAS Number 156907-84-5

PROPERTIES

Empirical Formula (Hill Notation) C15H23NO2S·HCl
Purity ≥98% (HPLC)
Apperance white to tan powder
Optical Rotation [α]/D -5 to -7°, c = 1 in methanol
Solubility H2O: ≥16 mg/mL
MSDS Link Download
Storage Temperature -20°C

DETAILS

Description (简体中文)
Legal Information
Sold for research purposes under agreement from Pfizer Inc.
Biochem/physiol Actions
OSU6162 (PNU-96391) is a dopamine stabilizer, a drug that can stimulate or inhibit dopaminergic signaling depending on the dopaminergic tone. Dopaminergic stabilizers have been proposed to act as partial dopamine receptor agonists or as antagonists with both dopamine and behavioral stabilizing activity. Although affinity is not high (in vitro binding affinity for dopamine D2 receptor has a Ki of 447 nM), OSU6162 shows a high level of receptor occupancy.

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