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Pemirolast potassium

Catalog No. SML0107 Name Sigma Aldrich
CAS Number 100299-08-9 Website http://www.sigmaaldrich.com
M. F. C10H7KN6O Telephone 1-800-521-8956
M. W. 266.30048 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 153257

SYNONYMS

IUPAC name
potassium 5-{9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}-1H-1,2,3,4-tetrazol-1-ide
IUPAC Traditional name
potassium 5-{9-methyl-4-oxopyrido[1,2-a]pyrimidin-3-yl}-1H-1,2,3,4-tetrazol-1-ide
Synonyms
9-Methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one potassium salt; BMY 26517

DATABASE IDS

CAS Number 100299-08-9

PROPERTIES

Empirical Formula (Hill Notation) C10H7N6O·K
Purity ≥98% (HPLC)
Apperance light yellow to yellow with a green cast powder
Solubility H2O: ≥18 mg/mL
MSDS Link Download
Storage Temperature 2-8°C

DETAILS

Description (简体中文)
Biochem/physiol Actions
Pemirolast potassium is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent. It Inhibits chemical mediator release from tissue mast cells and has recently also been shown to inhibit the release of peptides including substance P, neurokinin (NK) A, and calcitonin gene-related peptide (CGRP) from sensory nerves. It has been used for the treatment of allergic conjunctivitis prophylaxis of for pulmonary hypersensitivity reactions to drugs such as paclitaxel

REFERENCES