Pemirolast potassium

• Catalog No.: SML0107
• CAS Number: 100299-08-9
• M. F.: C10H7KN6O
• M. W.: 266.30048
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: potassium 5-{9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}-1H-1,2,3,4-tetrazol-1-ide
• IUPAC Traditional name: potassium 5-{9-methyl-4-oxopyrido[1,2-a]pyrimidin-3-yl}-1H-1,2,3,4-tetrazol-1-ide
• Synonyms: 9-Methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one potassium salt; BMY 26517

DATABASE IDS

• CAS Number: 100299-08-9

PROPERTIES

• Empirical Formula (Hill Notation): C10H7N6O·K
• Purity: ≥98% (HPLC)
• Apperance: light yellow to yellow with a green cast powder
• Solubility: H2O: ≥18 mg/mL
• Storage Temperature: 2-8°C

DETAILS

Description (简体中文)

Biochem/physiol Actions
Pemirolast potassium is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent. It Inhibits chemical mediator release from tissue mast cells and has recently also been shown to inhibit the release of peptides including substance P, neurokinin (NK) A, and calcitonin gene-related peptide (CGRP) from sensory nerves. It has been used for the treatment of allergic conjunctivitis prophylaxis of for pulmonary hypersensitivity reactions to drugs such as paclitaxel