Tubacin

• Catalog No.: SML0065
• CAS Number: 537049-40-4
• M. F.: C41H45N3O8S
• M. W.: 739.8763
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: N-{4-[(2R,4R,6S)-4-{[(diphenyl-1,3-oxazol-2-yl)sulfanyl]methyl}-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl}-N'-hydroxyoctanediamide hydrate
• IUPAC Traditional name: N-{4-[(2R,4R,6S)-4-{[(diphenyl-1,3-oxazol-2-yl)sulfanyl]methyl}-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl}-N'-hydroxyoctanediamide hydrate
• Synonyms: N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide

DATABASE IDS

• CAS Number: 537049-40-4

PROPERTIES

• Empirical Formula (Hill Notation): C41H43N3O7S
• Purity: ≥98% (HPLC)
• Shipped in: wet ice
• Apperance: white to tan powder
• Solubility: DMSO: ≥10 mg/mL
• Storage Condition: desiccated
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Tubacin is a selective inhibitor of histone deacetylase 6 (HDAC6), a predominantly cytoplasmic class II histone deacetylase that is involved in many cellular processes, including degradation of misfolded proteins, cell migration, and cell-cell interaction. Tubacin selectively inhibit HDAC6-mediated alpha -tubulin deacetylation.

Description (简体中文)

Biochem/physiol Actions
Tubacin is a selective inhibitor of histone deacetylase 6 (HDAC6), a predominantly cytoplasmic class II histone deacetylase that is involved in many cellular processes, including degradation of misfolded proteins, cell migration, and cell-cell interaction. Tubacin selectively inhibit HDAC6-mediated alpha -tubulin deacetylation.