ZM 241385

• Catalog No.: Z0153
• CAS Number: 139180-30-6
• M. F.: C16H15N7O2
• M. W.: 337.336
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol
• IUPAC Traditional name: 4-(2-{[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino}ethyl)phenol
• Synonyms: 4-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol

DATABASE IDS

• CAS Number: 139180-30-6
• MDL Number: MFCD00908394

PROPERTIES

• Empirical Formula (Hill Notation): C16H15N7O2
• Purity: ≥98% (HPLC)
• Apperance: white to tan powder
• Solubility: DMSO: >15 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• GHS Precautionary statements: P301 + P310
• Risk Statements: 25
• Safety Statements: 46
• Storage Temperature: room temp
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.

Description (简体中文)

Biochem/physiol Actions
ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.