O-(Octadecylphosphoryl)choline

• Catalog No.: 04449
• CAS Number: 65956-63-0
• M. F.: C23H50NO4P
• M. W.: 435.621161
• Purity: ≥98% (TLC)

SYNONYMS

• IUPAC name: octadecyl 2-(trimethylazaniumyl)ethyl phosphate
• IUPAC Traditional name: octadecyl 2-(trimethylammonio)ethyl phosphate
• Synonyms: Octadecylphosphocholine; Phosphocholine octadecyl ester

DATABASE IDS

• Beilstein Number: 3694312
• CAS Number: 65956-63-0
• MDL Number: MFCD00171405

PROPERTIES

• Empirical Formula (Hill Notation): C23H50NO4P
• Purity: ≥98% (TLC)
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Antitumor phospholipid3, induces apoptosis in three human leukemic cell lines4.
Biochem/physiol Actions
C18-phosphocholine was the most potent alkylphosphocholine tested in inhibiting phosphatidylcholine biosynthesis.1 The effect is mediated by interrupting the translocation of the rate-limiting enzyme, CTP:phosphocholine cytidylyltransferase, to membranes, where it is active.2

Description (简体中文)

Application
Antitumor phospholipid3, induces apoptosis in three human leukemic cell lines4.
Biochem/physiol Actions
C18-phosphocholine was the most potent alkylphosphocholine tested in inhibiting phosphatidylcholine biosynthesis.1 The effect is mediated by interrupting the translocation of the rate-limiting enzyme, CTP:phosphocholine cytidylyltransferase, to membranes, where it is active.2