BMS 493

• Catalog No.: B6688
• CAS Number: 215030-90-3
• M. F.: C29H24O2
• M. W.: 404.49966
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-{2-[5,5-dimethyl-8-(2-phenylethynyl)-5,6-dihydronaphthalen-2-yl]ethenyl}benzoic acid
• IUPAC Traditional name: 4-{2-[5,5-dimethyl-8-(2-phenylethynyl)-6H-naphthalen-2-yl]ethenyl}benzoic acid
• Synonyms: 4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(phenylethynyl)-2-naphthalenyl]ethenyl]-benzoic acid; BMS204, 493; (E)-4-[2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)naphthalen-2-yl]ethen-1-yl]benzoic acid

DATABASE IDS

• CAS Number: 215030-90-3
• MDL Number: MFCD17215944

PROPERTIES

• Empirical Formula (Hill Notation): C29H24O2
• Purity: ≥98% (HPLC)
• Apperance: light yellow to yellow powder
• Solubility: DMSO: ≥20 mg/mL
• GHS Hazard statements: H413
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
BMS 493 is an inverse pan-RAR agonist. Retinoic acid receptors (RARs) are ligand-dependent transcription factors that control a number of physiological processes. RARs exert their functions by regulating gene networks controlling cell growth, differentiation, survival, and death.

Description (简体中文)

Biochem/physiol Actions
BMS 493 is an inverse pan-RAR agonist. Retinoic acid receptors (RARs) are ligand-dependent transcription factors that control a number of physiological processes. RARs exert their functions by regulating gene networks controlling cell growth, differentiation, survival, and death.