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TNP

Catalog No. T3955 Name Sigma Aldrich
CAS Number 519178-28-0 Website http://www.sigmaaldrich.com
M. F. C20H16F3N7O2 Telephone 1-800-521-8956
M. W. 443.3819496 Fax
Purity ≥95% (HPLC) Email
Storage protect from light Chembase ID: 153219

SYNONYMS

IUPAC name
6-N-[(4-nitrophenyl)methyl]-2-N-{[3-(trifluoromethyl)phenyl]methyl}-9H-purine-2,6-diamine
IUPAC Traditional name
6-N-[(4-nitrophenyl)methyl]-2-N-{[3-(trifluoromethyl)phenyl]methyl}-9H-purine-2,6-diamine
Synonyms
N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine; N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

DATABASE IDS

MDL Number MFCD16875436
CAS Number 519178-28-0

PROPERTIES

Empirical Formula (Hill Notation) C20H16F3N7O2
Purity ≥95% (HPLC)
Apperance yellow powder
Solubility DMSO: ≥10 mg/mL
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H300-H319
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
GHS Precautionary statements P264-P301 + P310-P305 + P351 + P338
RID/ADR UN 2811 6.1/PG 3
Risk Statements 25-36
Safety Statements 26-45
Storage Condition protect from light
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.
Description (简体中文)
Biochem/physiol Actions
TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.

REFERENCES