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Nisoldipine

Catalog No. N0165 Name Sigma Aldrich
CAS Number 63675-72-9 Website http://www.sigmaaldrich.com
M. F. C20H24N2O6 Telephone 1-800-521-8956
M. W. 388.41436 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 284

SYNONYMS

IUPAC name
3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
IUPAC Traditional name
nisoldipino
Synonyms
1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-methylpropyl ester
Sular
(±)-Isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate

DATABASE IDS

EC Number 264-407-7
CAS Number 63675-72-9
MDL Number MFCD00478055

PROPERTIES

Empirical Formula (Hill Notation) C20H24N2O6
Purity ≥98% (HPLC)
Apperance yellow powder
Solubility DMSO: >10 mg/mL
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302-H312
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
GHS Precautionary statements P280
Risk Statements 20/21/22
RTECS US7975600
Safety Statements 36
Storage Temperature room temp
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
L-type (CaV1.2) calcium channel blocker; dihydropyridine-type calcium channel blocker with selectivity for smooth muscle (CaV1.2b) over cardiac muscle (CaV1.2a). Arterial vasodilator and antihypertensive agent.
Description (简体中文)
Biochem/physiol Actions
L-type (CaV1.2) calcium channel blocker; dihydropyridine-type calcium channel blocker with selectivity for smooth muscle (CaV1.2b) over cardiac muscle (CaV1.2a). Arterial vasodilator and antihypertensive agent.

REFERENCES