AFMK

• Catalog No.: A2355
• CAS Number: 52450-38-1
• M. F.: C13H16N2O4
• M. W.: 264.27714
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: N-[3-(2-formamido-5-methoxyphenyl)-3-oxopropyl]acetamide
• IUPAC Traditional name: N-[3-(2-formamido-5-methoxyphenyl)-3-oxopropyl]acetamide
• Synonyms: N-[3-[2-(Formylamino)-5-methoxyphenyl]-3-oxopropyl]acetamide; NSC 688263

DATABASE IDS

• CAS Number: 52450-38-1
• PubChem SID: 24724387
• MDL Number: MFCD02683241

PROPERTIES

• Empirical Formula (Hill Notation): C13H16N2O4
• Purity: ≥98% (HPLC)
• Apperance: white solid
• Solubility: DMSO: >10 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H319
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310-P305 + P351 + P338
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25
• Safety Statements: 45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
AFMK is a melatonin metabolite first detected in rat brain; demonstrates antioxidant and free radical scavenging activities in several experimental models; inhibits LPS-mediated production of TNFα and IL-8 in neutrophils; useful tool in the study of melatonin metabolism.

Description (简体中文)

Biochem/physiol Actions
AFMK is a melatonin metabolite first detected in rat brain; demonstrates antioxidant and free radical scavenging activities in several experimental models; inhibits LPS-mediated production of TNFα and IL-8 in neutrophils; useful tool in the study of melatonin metabolism.