D-Fructose 1,6-bisphosphate trisodium salt hydrate

• Catalog No.: F6803
• CAS Number: 38099-82-0(anhydrous)
• M. F.: C6H13Na3O13P2
• M. W.: 424.076452
• Purity: ≥98% (TLC)

SYNONYMS

• IUPAC name: trisodium hydrate (3S,4R,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonatooxy)hexyl hydrogen phosphate
• IUPAC Traditional name: trisodium hydrate (3S,4R,5R)-3,4,5-trihydroxy-2-oxo-6-(phosphonatooxy)hexyl hydrogen phosphate
• Synonyms: Harden-Young ester; Hexose diphosphate trisodium salt hydrate; D(+)Fructofuranose 1,6-diphosphate trisodium salt hydrate

DATABASE IDS

• CAS Number: 38099-82-0(anhydrous)
• PubChem SID: 24894921
• MDL Number: MFCD03427650

PROPERTIES

• Empirical Formula (Hill Notation): C6H11Na3O12P2 · xH2O
• Purity: ≥98% (TLC)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Packaging
10 mg in autosample vial
Biochem/physiol Actions
Fructose-1,6-biphosphate (F1,6P) is a glycolytic intermediate produced by the transfer of a phosphate from ATP to fructose-6-phosphate by the enzyme phosphofructokinase. Fructose-1,6-biphosphate, along with fructose-2,6-biphosphate, modulates the activity of phosphofructokinase-1 (PFK-1), the rate-limiting step in glycolysis. During glycolysis, aldolase splits Fructose-1,6-biphosphate into dihydroxacetone phosphate (DHAP) and glyceraldehyde phosphate. Fructose-1,6-biphosphate is also an allosteric activator of the M2 isoform of Pyruvate Kinase (PK-M2), the predominant form of pyruvate kinase in cancer cells.

Description (简体中文)

包装
10 mg in autosmp vl
Biochem/physiol Actions
Fructose-1,6-biphosphate (F1,6P) is a glycolytic intermediate produced by the transfer of a phosphate from ATP to fructose-6-phosphate by the enzyme phosphofructokinase. Fructose-1,6-biphosphate, along with fructose-2,6-biphosphate, modulates the activity of phosphofructokinase-1 (PFK-1), the rate-limiting step in glycolysis. During glycolysis, aldolase splits Fructose-1,6-biphosphate into dihydroxacetone phosphate (DHAP) and glyceraldehyde phosphate. Fructose-1,6-biphosphate is also an allosteric activator of the M2 isoform of Pyruvate Kinase (PK-M2), the predominant form of pyruvate kinase in cancer cells.