8-MA-cAMP

• Catalog No.: P0747
• CAS Number: 33823-18-6
• M. F.: C11H14N6NaO6P
• M. W.: 380.228991
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: sodium (4aR,6R,7R,7aS)-6-[6-amino-8-(methylamino)-9H-purin-9-yl]-7-hydroxy-2-oxo-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-olate
• IUPAC Traditional name: sodium (4aR,6R,7R,7aS)-6-[6-amino-8-(methylamino)purin-9-yl]-7-hydroxy-2-oxo-tetrahydro-4H-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-olate
• Synonyms: 8-Methylaminoadenosine-3′,5′-cyclic monophosphate sodium salt

DATABASE IDS

• MDL Number: MFCD04113731
• CAS Number: 33823-18-6
• PubChem SID: 24724571

PROPERTIES

• Empirical Formula (Hill Notation): C11H14N6O6PNa
• Packaging: pkg of 10 μmol
• Purity: ≥98% (HPLC)
• Shipped in: dry ice
• Apperance: white solid
• Solubility: H2O: freely soluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -70°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Selective cAMP-dependent protein kinase (PKA) activator. Site selective cyclic AMP analogue with similar affinity to site B of both protein kinase A type I and II. Priming analogue which acts synergistically together with analogues showing site A preference. Together with e.g. 8-piperidino cAMP, selective stimulation of type I can be achieved.

Description (简体中文)

Biochem/physiol Actions
Selective cAMP-dependent protein kinase (PKA) activator. Site selective cyclic AMP analogue with similar affinity to site B of both protein kinase A type I and II. Priming analogue which acts synergistically together with analogues showing site A preference. Together with e.g. 8-piperidino cAMP, selective stimulation of type I can be achieved.