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8-MA-cAMP_Molecular_structure_CAS_33823-18-6)
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8-MA-cAMP

Catalog No. P0747 Name Sigma Aldrich
CAS Number 33823-18-6 Website http://www.sigmaaldrich.com
M. F. C11H14N6NaO6P Telephone 1-800-521-8956
M. W. 380.228991 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 153188

SYNONYMS

IUPAC name
sodium (4aR,6R,7R,7aS)-6-[6-amino-8-(methylamino)-9H-purin-9-yl]-7-hydroxy-2-oxo-hexahydro-1,3,5,2λ5-furo[3,2-d][1,3,2λ5]dioxaphosphinin-2-olate
IUPAC Traditional name
sodium (4aR,6R,7R,7aS)-6-[6-amino-8-(methylamino)purin-9-yl]-7-hydroxy-2-oxo-tetrahydro-4H-1,3,5,2λ5-furo[3,2-d][1,3,2λ5]dioxaphosphinin-2-olate
Synonyms
8-Methylaminoadenosine-3′,5′-cyclic monophosphate sodium salt

DATABASE IDS

MDL Number MFCD04113731
CAS Number 33823-18-6
PubChem SID 24724571

PROPERTIES

Empirical Formula (Hill Notation) C11H14N6O6PNa
Packaging pkg of 10 μmol
Purity ≥98% (HPLC)
Shipped in dry ice
Apperance white solid
Solubility H2O: freely soluble
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -70°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Selective cAMP-dependent protein kinase (PKA) activator. Site selective cyclic AMP analogue with similar affinity to site B of both protein kinase A type I and II. Priming analogue which acts synergistically together with analogues showing site A preference. Together with e.g. 8-piperidino cAMP, selective stimulation of type I can be achieved.
Description (简体中文)
Biochem/physiol Actions
Selective cAMP-dependent protein kinase (PKA) activator. Site selective cyclic AMP analogue with similar affinity to site B of both protein kinase A type I and II. Priming analogue which acts synergistically together with analogues showing site A preference. Together with e.g. 8-piperidino cAMP, selective stimulation of type I can be achieved.

REFERENCES