SD-169

• Catalog No.: S0572
• CAS Number: 1670-87-7
• M. F.: C9H8N2O
• M. W.: 160.17262
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 1H-indole-5-carboxamide
• IUPAC Traditional name: indole-5-carboxamide
• Synonyms: indole-5-carboxamide

DATABASE IDS

• PubChem SID: 24724600
• CAS Number: 1670-87-7
• MDL Number: MFCD07779486

PROPERTIES

• Empirical Formula (Hill Notation): C9H8N2O
• Purity: ≥98% (HPLC)
• Apperance: white solid
• Solubility: DMSO: ~18 mg/mL
• Solubility: H2O: <2 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 22-36/37/38
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
SD-169 is an orally active, ATP-competitve, p38α-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. SD-169 demonstrates 38-fold potency against p38α MAP kinase (IC50 = 3.2 nM) than p38β MAP kinase (IC50 = 122 nM).

Description (简体中文)

Biochem/physiol Actions
SD-169 is an orally active, ATP-competitve, p38α-selective Mitogen-Activated Protein Kinase (MAPK) inhibitor. SD-169 demonstrates 38-fold potency against p38α MAP kinase (IC50 = 3.2 nM) than p38β MAP kinase (IC50 = 122 nM).