(+)-Norfenfluramine hydrochloride

• Catalog No.: N3288
• CAS Number: 37936-89-3
• M. F.: C10H13ClF3N
• M. W.: 239.6651296
• Purity: ≥98% (HPLC)

SYNONYMS

• Title: (+)-Norfenfluramine 盐酸盐
• IUPAC name: (2S)-1-[3-(trifluoromethyl)phenyl]propan-2-amine hydrochloride
• IUPAC Traditional name: (2S)-1-[3-(trifluoromethyl)phenyl]propan-2-amine hydrochloride
• Synonyms: S-(+)-α-Methyl-3-(trifluoromethyl)benzeneethanamine hydrochloride; JP 92; S-(+)-α-Methyl-3-(trifluoromethyl)benzeneethanamine 盐酸盐; NSC 43036

DATABASE IDS

• MDL Number: MFCD11045299
• CAS Number: 37936-89-3

PROPERTIES

• Empirical Formula (Hill Notation): C10H12F3N · HCl
• Purity: ≥98% (HPLC)
• Apperance: white powder
• Solubility: H2O: >10 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36/37
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
(+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release.

Description (简体中文)

Biochem/physiol Actions
(+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release.