Metolazone

• Catalog No.: M1195
• CAS Number: 17560-51-9
• M. F.: C16H16ClN3O3S
• M. W.: 365.83454
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
• IUPAC Traditional name: metolazone
• Synonyms: 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide

DATABASE IDS

• PubChem SID: 24724532
• CAS Number: 17560-51-9
• MDL Number: MFCD00069304
• EC Number: 241-539-3

PROPERTIES

• Empirical Formula (Hill Notation): C16H16ClN3O3S
• Purity: ≥98% (HPLC)
• Gene Information: human ... SLC12A1(6557)
• Apperance: white solid
• Solubility: DMSO: >5 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: VA1700000
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Inhibitor of thiazide-sensitive Na+-Cl- cotransporter; antihypertensive; moderate "loop" diuretic.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M1195.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Description (简体中文)

Biochem/physiol Actions
Inhibitor of thiazide-sensitive Na+-Cl- cotransporter; antihypertensive; moderate "loop" diuretic.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M1195.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.