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R5C3

Catalog No. R7529 Name Sigma Aldrich
CAS Number 753504-14-2 Website http://www.sigmaaldrich.com
M. F. C33H28N2O6 Telephone 1-800-521-8956
M. W. 548.58522 Fax
Purity ≥97% (HPLC) Email
Storage Chembase ID: 153146

SYNONYMS

IUPAC name
3-{1-[(benzyloxy)carbonyl]-5-methyl-1H-indol-3-yl}-2-[(2-phenoxyphenyl)formamido]propanoic acid
IUPAC Traditional name
3-{1-[(benzyloxy)carbonyl]-5-methylindol-3-yl}-2-[(2-phenoxyphenyl)formamido]propanoic acid
Synonyms
5-Methyl-N-(2-phenoxybenzoyl)-1-[(phenylmethoxy)carbonyl]-D/L-tryptophan

DATABASE IDS

MDL Number MFCD08705330
PubChem SID 24724593
CAS Number 753504-14-2

PROPERTIES

Empirical Formula (Hill Notation) C33H28N2O6
Purity ≥97% (HPLC)
Apperance solid
Solubility DMSO: soluble18 mg/mL
MSDS Link Download
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
R5C3 is an MDM2 inhibitor, 2-phenoxybenzoyl-tryptophan derivative. Reported as a novel probe for high throughput fluorescence polarization binding assay. Useful in drug screening for small molecule inhibitors of MDM2-binding to p53.
Description (简体中文)
Biochem/physiol Actions
R5C3 is an MDM2 inhibitor, 2-phenoxybenzoyl-tryptophan derivative. Reported as a novel probe for high throughput fluorescence polarization binding assay. Useful in drug screening for small molecule inhibitors of MDM2-binding to p53.

REFERENCES