AC-55649

• Catalog No.: A9480
• CAS Number: 59662-49-6
• M. F.: C21H26O2
• M. W.: 310.42994
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-(4-octylphenyl)benzoic acid
• IUPAC Traditional name: 4-(4-octylphenyl)benzoic acid
• Synonyms: 4′-Octyl-4-biphenylcarboxylic acid, 4′-n-octylbiphenyl-4-carboxylic acid; 8BCA

DATABASE IDS

• PubChem SID: 24724405
• MDL Number: MFCD00157040
• CAS Number: 59662-49-6

PROPERTIES

• Empirical Formula (Hill Notation): C21H26O2
• Purity: ≥98% (HPLC)
• Gene Information: human ... RARB(5915)
• Apperance: solid
• Solubility: DMSO: >7 mg/mL
• GHS Hazard statements: H413
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
AC-55649 is a subtype selective RAR (RARβ2) agonist. AC-55649 is a potent, orally available isoform selective Retinoic Acid Receptor β2. AC-55649 has high selectivity, 99% for RARβ2 and 31% for RARβ1. When compared to the gold standard AM-580 (Cat. No A8843), both isoform receptors were 100%. AC-55649 has a potent EC50 of 6.9 μM compared to an EC50 of 7.7 μM for AM-580.

Description (简体中文)

Biochem/physiol Actions
AC-55649 is a subtype selective RAR (RARβ2) agonist. AC-55649 is a potent, orally available isoform selective Retinoic Acid Receptor β2. AC-55649 has high selectivity, 99% for RARβ2 and 31% for RARβ1. When compared to the gold standard AM-580 (Cat. No A8843), both isoform receptors were 100%. AC-55649 has a potent EC50 of 6.9 μM compared to an EC50 of 7.7 μM for AM-580.