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Ibudilast

Catalog No. I0157 Name Sigma Aldrich
CAS Number 50847-11-5 Website http://www.sigmaaldrich.com
M. F. C14H18N2O Telephone 1-800-521-8956
M. W. 230.30552 Fax
Purity ≥99% (HPLC) Email
Storage Chembase ID: 4411

SYNONYMS

IUPAC name
2-methyl-1-[2-(propan-2-yl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one
IUPAC Traditional name
ibudilast
Synonyms
3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine
KC-404
2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl] 1-propanone

DATABASE IDS

MDL Number MFCD00864808
CAS Number 50847-11-5
PubChem SID 24278482

PROPERTIES

Empirical Formula (Hill Notation) C14 H18 N2 O
Purity ≥99% (HPLC)
Gene Information human ... PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144)
Apperance white solid
Solubility DMSO: soluble28 mg/mL
Solubility H2O: soluble4.5 mg/mL
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302-H315-H319-H335
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 22-36/37/38
RTECS UR0711200
Safety Statements 26-36
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Phosphodiesterase IV (PDE4) inhbitor. Inhibits platelet aggregation. Anti-asthma drug.
Description (简体中文)
Biochem/physiol Actions
Phosphodiesterase IV (PDE4) inhbitor. Inhibits platelet aggregation. Anti-asthma drug.

REFERENCES