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Fluo 3-AM

Catalog No. 46394 Name Sigma Aldrich
CAS Number 121714-22-5 Website http://www.sigmaaldrich.com
M. F. C51H50Cl2N2O23 Telephone 1-800-521-8956
M. W. 1129.8483 Fax
Purity Email
Storage Chembase ID: 153095

SYNONYMS

IUPAC name
(acetyloxy)methyl 2-({2-[2-(5-{6-[(acetyloxy)methoxy]-2,7-dichloro-3-oxo-3H-xanthen-9-yl}-2-[bis({2-[(acetyloxy)methoxy]-2-oxoethyl})amino]phenoxy)ethoxy]-4-methylphenyl}({2-[(acetyloxy)methoxy]-2-oxoethyl})amino)acetate
IUPAC Traditional name
(acetyloxy)methyl 2-({2-[2-(5-{3-[(acetyloxy)methoxy]-2,7-dichloro-6-oxoxanthen-9-yl}-2-[bis({2-[(acetyloxy)methoxy]-2-oxoethyl})amino]phenoxy)ethoxy]-4-methylphenyl}({2-[(acetyloxy)methoxy]-2-oxoethyl})amino)acetate
Synonyms
4-(6-Acetoxymethoxy-2,7-dichloro-3-oxo-9-xanthenyl)-4′-methyl-2,2′(ethylenedioxy)dianiline-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl) ester

DATABASE IDS

CAS Number 121714-22-5
PubChem SID 24870122

PROPERTIES

Empirical Formula (Hill Notation) C51H50Cl2N2O23
Suitability suitable for fluorescence
Fluorescence λex 506 nm; λem 526 nm in 0.1 M Tris pH 8.0, esterase 30 mM Ca2+
Solubility DMSO: soluble
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Application
Cell permeable fluorescent indicator of intracellular Ca2+; non-fluorescent until it is hydrolyzed intracellularly and/or in the presence of Ca2+; lower binding affinity allows measurement of higher peaks of Ca2+ transients than with Fura 2.
Description (简体中文)
Application
Cell permeable fluorescent indicator of intracellular Ca2+; non-fluorescent until it is hydrolyzed intracellularly and/or in the presence of Ca2+; lower binding affinity allows measurement of higher peaks of Ca2+ transients than with Fura 2.

REFERENCES