Hoveyda-Grubbs Catalyst 1st Generation

• Catalog No.: 577944
• CAS Number: 203714-71-0
• M. F.: C28H45Cl2OPRu
• M. W.: 600.606061

SYNONYMS

• Title: 第 1 代 Hoveyda-Grubbs 催化剂
• IUPAC name: dichloro({[2-(propan-2-yloxy)phenyl]methylidene})ruthenium; tricyclohexylphosphane
• IUPAC Traditional name: dichloro[(2-isopropoxyphenyl)methylidene]ruthenium; tricyclohexylphosphine
• Synonyms: 二氯(邻异丙氧基苯基亚甲基)(三环己基膦)钌(II); Dichloro(o-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium(II)

DATABASE IDS

• PubChem SID: 24880901
• MDL Number: MFCD03453042
• CAS Number: 203714-71-0

PROPERTIES

• Empirical Formula (Hill Notation): C28H45Cl2OPRu
• Melting Point: 195-197 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H228
• European Hazard Symbols: Flammable (F)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• GHS Precautionary statements: P210
• Risk Statements: 11
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Metathesis: Ruthenium-Based Metathesis Catalysts
Hoveyda-Grubbs 1st Generation CatalystSimilar reactivity to the Grubbs 1st Generation Catalyst. Proven to be useful in Ring-Closing Metathesis (RCM) to form macrocycles.Catalyst used in ring-closing metathesis with concomitant cis-vicinal dihyroxylation. Also employed in a pivotal, macrocyclic ring-closing metathesis in the multi-step synthesis of an HCV protease inhibitor.
Olefin metathesis catalyst.
Other Notes
NO BULK ORDERS
Packaging
100, 500 mg in glass bottle
2 g in glass bottle
Legal Information
Sale of this product conveys to the buyer a limited-use research license. For full details of this license please see sigma-aldrich.com/materialicense. For questions, please contact us at aldrich@sial.com or Materia at info@materia-inc.com

Description (简体中文)

Application
Metathesis: Ruthenium-Based Metathesis Catalysts
烯烃复分解催化剂。
用于闭环复分解反应并伴随顺式-邻双羟基化反应的催化剂。还用于多步合成丙型肝炎病毒蛋白酶抑制剂中关键的大环闭环复分解反应。
Other Notes
不接受批量订单
包装
100, 500 mg in glass bottle
2 g in glass bottle
Legal Information
如购买该产品，我们将为购买者寄出限制适用研究许可。有关该许可的完整详细内容，请访问 sigma-aldrich.com/materialicense。如有疑问，请发送电子邮件至 aldrich@sial.com 与我们联系，或发送至 info@materia-inc.com 联系 Materia。