tert-Butoxy bis(dimethylamino)methane

• Catalog No.: 20425
• CAS Number: 5815-08-7
• M. F.: C9H22N2O
• M. W.: 174.28378

SYNONYMS

• Title: 叔丁氧基双(二甲胺基)甲烷
• IUPAC name: [(tert-butoxy)(dimethylamino)methyl]dimethylamine
• IUPAC Traditional name: [tert-butoxy(dimethylamino)methyl]dimethylamine
• Synonyms: Bredereck 试剂; Bredereck’s reagent

DATABASE IDS

• MDL Number: MFCD00042858
• CAS Number: 5815-08-7
• PubChem SID: 24852244
• Beilstein Number: 1901973
• EC Number: 227-383-9

PROPERTIES

• Grade: technical
• Linear Formula: (CH3)3COCH[N(CH3)2]2
• Boiling Point: 50-55 °C/15 mmHg(lit.)
• Density: 0.844 g/mL at 25 °C(lit.)
• Flash Point: 41 °C
• Flash Point: 105.8 °F
• Refractive Index: n20/D 1.422(lit.)
• Refractive Index: n20/D 1.422
• GHS Signal Word: Warning
• GHS Hazard statements: H226-H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P261-P305 + P351 + P338
• RID/ADR: UN 1993 3/PG 3
• Risk Statements: 10-36/37/38
• Safety Statements: 26
• Hazard Class: 3
• UN Number: 1993
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Analysis Note
mixture of tert-Butoxy bis(dimethylamino)methane, tris(dimethylamino)methane and N,N-Dimethylformamide di-tert-butyl acetal
Other Notes
Review5; Mild condensation reactions6
Packaging
10, 50 mL in glass bottle
Application
Reactant for:
• Preparation of pyrroloquinazolines as photochemotherapeutic agents1
• Enanatioslective formal synthesis of the Cinchona alkaloid quinine via stereoselective intermolecular radical addition2
• Synthesis of camptothecin via intramolecular isomuenchnone cycloaddition reaction3
• Aminomethylenation reactions4

Description (简体中文)

Analysis Note
叔丁氧基双(二甲胺基)甲烷、三(二甲胺基)甲烷和N,N-二甲基甲酰胺二叔丁基乙缩醛的混合物
Other Notes
综述5；条件温和的缩合反应6
包装
10, 50 mL in glass bottle
Application
Reactant for:
• Preparation of pyrroloquinazolines as photochemotherapeutic agents1
• Enanatioslective formal synthesis of the Cinchona alkaloid quinine via stereoselective intermolecular radical addition2
• Synthesis of camptothecin via intramolecular isomuenchnone cycloaddition reaction3
• Aminomethylenation reactions4