Harmaline

• Catalog No.: 51330
• CAS Number: 304-21-2
• M. F.: C13H14N2O
• M. W.: 214.26306

SYNONYMS

• Title: 骆驼蓬灵
• IUPAC name: 7-methoxy-1-methyl-3H,4H,9H-pyrido[3,4-b]indole
• IUPAC Traditional name: harmaline
• Synonyms: Dihydroharmine; 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole; 7-甲氧基-1-甲基-4,9-二氢-3H-吡啶并[3,4-b]吲哚; 1-Methyl-7-methoxy-3,4-dihydro-β-carboline; Harmalol methyl ether; NSC 407285; Harmidine; 1-甲基-7-甲氧基-3,4-二氢-β-咔啉; 3,4-二氢骆驼蓬碱; O-甲基骆驼蓬酚

DATABASE IDS

• Beilstein Number: 207310
• CAS Number: 304-21-2
• PubChem SID: 24873687
• MDL Number: MFCD00004955
• EC Number: 206-152-6

PROPERTIES

• German water hazard class: 3
• Drug Control: stupéfiantregulated under CDSA - not available from Sigma-Aldrich Canada
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: UU9800000
• Empirical Formula (Hill Notation): C13H14N2O
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133), DRD1(1812), DRD5(1816), HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR2C(3358), HTR3A(3359), HTR5A(3361), HTR6(3362), HTR7(3363), SLC6A2(6530), SLC6A4(6532), SLC9A2(6549), SLC9A5(6553)rat ... Drd2(24318), Drd3(29238), Drd4(25432), Htr2a(29595), Maoa(29253), Maob(25750), Slc9a1(24782), Slc9a3(24784)
• Melting Point: 232-234 °C(lit.)

DETAILS

Description (English)

Biochem/physiol Actions
CNS stimulant; may act through NMDA receptors
Packaging
1 g in glass bottle
Application
Reactant for preparation of:
• Acylated harmalines via Friedel-Crafts reaction1
• Phenacyl derivatives of 1-methyl-7-methoxy-β-carbolines as central nervous system affectors2
• Palladium harmaline DMSO chloro complex as anti-tumor agent3Natural product scaffold in preparation of:
• Trypanothione reductase inhibitors†

Description (简体中文)

Biochem/physiol Actions
中枢神经系统兴奋剂；可通过 NMDA 受体起作用
包装
1 g in glass bottle
Application
Reactant for preparation of:
• Acylated harmalines via Friedel-Crafts reaction1
• Phenacyl derivatives of 1-methyl-7-methoxy-β-carbolines as central nervous system affectors2
• Palladium harmaline DMSO chloro complex as anti-tumor agent3Natural product scaffold in preparation of:
• Trypanothione reductase inhibitors†