1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

• Catalog No.: 41661
• CAS Number: 7226-23-5
• M. F.: C6H12N2O
• M. W.: 128.17228
• Purity: ≥99.0% (GC)

SYNONYMS

• Title: 1,3-甲基-3,4,5,6-四氢-2(1H)-嘧啶酮
• IUPAC name: 1,3-dimethyl-1,3-diazinan-2-one
• IUPAC Traditional name: DMPU
• Synonyms: N,N′-Dimethylpropylene urea; 1,3-Dimethyl-2-oxohexahydropyrimidine; DMPU; N,N-二甲基丙烯基脲

DATABASE IDS

• PubChem SID: 24865915
• CAS Number: 7226-23-5
• Beilstein Number: 110562
• MDL Number: MFCD00006550
• EC Number: 230-625-6

PROPERTIES

• Empirical Formula (Hill Notation): C6H12N2O
• Grade: absolute
• Purity: ≥99.0% (GC)
• Quality: over molecular sieve (H2O ≤0.03%)
• Boiling Point: 146 °C/44 mmHg(lit.)
• Density: 1.06 g/mL at 25 °C(lit.)
• Flash Point: 120 °C
• Flash Point: 248 °F
• Refractive Index: n20/D 1.488(lit.)
• Refractive Index: n20/D 1.489
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H318-H361f
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P280-P305 + P351 + P338
• Risk Statements: 22-36-43
• RTECS: UW7582500
• Safety Statements: 23-26-36/37/39
• German water hazard class: 2

DETAILS

Description (English)

Other Notes
Aprotic, dipolar solvent, which is an excellent replacement of the carcinogenic HMPA as cosolvent for highly reactive nucleophiles and bases. High Z-selectivity in enolate formation;1,2 DMPU was shown to be non-mutagenic and safe.3
Packaging
1 L in Sure/Seal™
250 mL in Sure/Seal™

Description (简体中文)

Other Notes
偶极非质子溶剂，可有效替代致癌的 HMPA，作为高反应性亲核试剂和碱的助溶剂。在烯醇化物形成中具有高 Z-选择性；1,2DMPU 显示出非诱变性和安全性。3
包装
1 L in Sure/Seal™
250 mL in Sure/Seal™