N,N-Bis(phosphonomethyl)glycine

• Catalog No.: 15149
• CAS Number: 2439-99-8
• M. F.: C4H11NO8P2
• M. W.: 263.079562
• Purity: ≥98.0% (T)

SYNONYMS

• Title: N,N-双(膦羟甲基)甘氨酸
• IUPAC name: 2-[bis(phosphonomethyl)amino]acetic acid
• IUPAC Traditional name: glyphosine
• Synonyms: 增甘磷; N-(Carboxymethyl)iminodi(methylphosphinic acid); Glyphosine

DATABASE IDS

• EC Number: 219-468-4
• Beilstein Number: 1884944
• CAS Number: 2439-99-8
• MDL Number: MFCD00056670

PROPERTIES

• Empirical Formula (Hill Notation): C4H11NO8P2
• Purity: ≥98.0% (T)
• GHS Signal Word: Danger
• GHS Hazard statements: H318
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P280-P305 + P351 + P338
• RID/ADR: UN 3261 8/PG 3
• Risk Statements: 41
• RTECS: MB9120000
• Safety Statements: 26
• Hazard Class: 8
• UN Number: 3261
• Packing Group: 3
• German water hazard class: 1

DETAILS

Description (English)

Biochem/physiol Actions
Anti-diabetic; delay onset of diabetes in non-obese NOD mice1
Packaging
10, 50 g in poly bottle
Application
Application: Complexing agent; pK-values: pK1: ·2, pK2: 2.0, pK3: 5.20, pK4: 6.77, pK5: 10.89 Anti-diabetic; delay onset of diabetes in non-obese NOD miceGlyphosine binds to a pocket of MHC class II molecules I-Ag7 and DQ8, and modify T cell responses to the autoantigenic insulin B chain fragment 9-23 (B:9-23) peptide. Glyphosine stimulate IL-10 production and delay onset of diabetes in non-obese NOD mice.†

Description (简体中文)

Biochem/physiol Actions
Anti-diabetic; delay onset of diabetes in non-obese NOD mice1
包装
10, 50 g in poly bottle
Application
络合剂；pK 值：pK1：≤2，pK2：2.0，pK3：5.20，pK4：6.77，pK5：10.89