Quinidine

• Catalog No.: 22600
• CAS Number: 56-54-2
• M. F.: C20H24N2O2
• M. W.: 324.41676
• Purity: ≥98.0% (dried material, NT)

SYNONYMS

• Title: 奎尼丁
• IUPAC name: (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol
• IUPAC Traditional name: quinidine

DATABASE IDS

• EC Number: 200-279-0
• PubChem SID: 24853537
• MDL Number: MFCD00135581
• CAS Number: 56-54-2
• Beilstein Number: 91866

PROPERTIES

• Empirical Formula (Hill Notation): C20H24N2O2
• Impurities: ≤2% water
• Impurities: ~10% hydroquinidine (HPLC)
• Purity: ≥98.0% (dried material, NT)
• Quality: crystallized
• Gene Information: human ... ABCB1(5243), CYP2D6(1565), CYP3A4(1576), KCNH1(3756)mouse ... Abcb1a(18671), Abcb1b(18669)rat ... Cyp2d1(266684), Cyp2d2(25053), Cyp2d3(24303), Cyp2d4v1(171522)
• Melting Point: 168-172 °C(lit.)
• Optical Rotation: [α]20/D +265±5°, c = 0.8% in ethanol (dry matter)
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 22
• RTECS: VA4725000
• Safety Statements: 36
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Class IA antiarrhythmic; potassium channel blocker.
Other Notes
Chiral catalyst, used e.g. in highly enantioselective [2+2] cycloadditions1,2,3
Packaging
10, 50 g in poly bottle

Description (简体中文)

Biochem/physiol Actions
IA 类抗心律失常药；钾通道阻断剂。
Other Notes
手性催化剂，用于，例如，高度不对称 [2+2] 环加成反应1,2,3
包装
10, 50 g in poly bottle