Trichloromethyl chloroformate

• Catalog No.: 23261
• CAS Number: 503-38-8
• M. F.: C2Cl4O2
• M. W.: 197.8322
• Purity: ≥97.0% (GC)

SYNONYMS

• Title: 氯甲酸三氯甲酯
• IUPAC name: trichloromethyl chloroformate
• IUPAC Traditional name: trichloromethyl chloroformate
• Synonyms: 氯代甲酸三氯甲酯; di-Phosgene; Diphosgene; 双光气

DATABASE IDS

• CAS Number: 503-38-8
• EC Number: 207-965-9
• Beilstein Number: 970225
• MDL Number: MFCD00015553
• PubChem SID: 24853917

PROPERTIES

• Linear Formula: ClCOOCCl3
• Purity: ≥97.0% (GC)
• Boiling Point: 20 °C/10 mmHg(lit.)
• Density: 1.639 g/mL at 20 °C
• Refractive Index: n20/D 1.458
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H314-H330
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P260-P264-P280-P284-P301 + P310-P305 + P351 + P338
• RID/ADR: UN 3277 6.1/PG 2
• Risk Statements: 26/28-34
• RTECS: LQ7350000
• Safety Statements: 26-28-36/37/39-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 3277
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Easy to handle substitute for phosgene7,8,9; In-situ charcoal-catalyzed decomposition to phosgene and reaction with amino acids to N-carboxy anhydrides10
Packaging
10, 50 mL in glass bottle
Application
Reactant for preparation of:
• Cyclic carbamimidates using a monophosphine gold(i) catalyst1
• N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands2
• Prostate-specific membrane antigen-targeted anticancer prodrugs3
• Potential west nile virus protease inhibitors4
• Antibody-drug conjugates (ADCs)5
• Erythromycin A derivatives6

Description (简体中文)

Other Notes
光气的易处理替代品7,8,9；可通过原位炭催化分解成光气，并可与氨基酸反应生成 N-羧酸酐10
包装
10, 50 mL in glass bottle
Application
Reactant for preparation of:
• Cyclic carbamimidates using a monophosphine gold(i) catalyst1
• N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands2
• Prostate-specific membrane antigen-targeted anticancer prodrugs3
• Potential west nile virus protease inhibitors4
• Antibody-drug conjugates (ADCs)5
• Erythromycin A derivatives6