N,N-Dimethylmethyleneiminium chloride

• Catalog No.: 40766
• CAS Number: 30354-18-8
• M. F.: C3H8ClN
• M. W.: 93.55532
• Purity: ≥95.0% (AT)

SYNONYMS

• Title: N,N-二甲基氯烯亚胺
• IUPAC name: dimethyl(methylidene)azanium chloride
• IUPAC Traditional name: dimethyl(methylidene)azanium chloride
• Synonyms: Eschenmoser 盐; Eschenmoser’s salt; Methylenedimethylammonium chloride; Dimethylformiminium chloride

DATABASE IDS

• EC Number: 250-142-4
• CAS Number: 30354-18-8
• Beilstein Number: 505955
• MDL Number: MFCD00011809
• PubChem SID: 24865473

PROPERTIES

• Linear Formula: CH2=N+(CH3)2Cl-
• Purity: ≥95.0% (AT)
• Flash Point: 82 °C
• Flash Point: 179.6 °F
• Melting Point: 146-148 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H228-H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P210-P261-P305 + P351 + P338
• RID/ADR: UN 1325 4.1/PG 3
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Hazard Class: 4.1
• UN Number: 1325
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
"Mannich-reagent" for direct use; higher yields of purer products were achieved in shorter times compared with the classical "Mannich reaction"7,8,9; in-situ preparation of the reactive triflate with TMS-triflate10
Packaging
5, 25 g in glass bottle
Application
Reacant for:Preparation of dihydronaphthyridinones as HIV-1 integrase inhibitors1Mannich reactions2Preparation of cyanotetrahydrooxo-β-carbolines via cyclocondensation reactions3Asymmetric synthesis of phalarine via stereospecific Pictet-Spengler cyclocondensation and traceless chirality transfer from L-tryptophan4Synthesis of functionalized diarylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LOX)5Synthesis of (±)-phalarine with the rearrangement of an azaspiroindolenine and Gassman oxindole preparation as key steps6

Description (简体中文)

Other Notes
供直接使用的"Mannich 试剂"；与传统的"Mannich 反应"相比，可在更短时间内生成产量和纯度更高的产物7,8,9；与三氟甲磺酸三甲基硅酯原位制备反应性三氟甲磺酸盐10
包装
5, 25 g in glass bottle
Application
Reacant for:Preparation of dihydronaphthyridinones as HIV-1 integrase inhibitors1Mannich reactions2Preparation of cyanotetrahydrooxo-β-carbolines via cyclocondensation reactions3Asymmetric synthesis of phalarine via stereospecific Pictet-Spengler cyclocondensation and traceless chirality transfer from L-tryptophan4Synthesis of functionalized diarylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LOX)5Synthesis of (±)-phalarine with the rearrangement of an azaspiroindolenine and Gassman oxindole preparation as key steps6