(R)-1-Ethyl hydrogen 3-methylglutarate

• Catalog No.: 67000
• CAS Number: 72594-19-5
• M. F.: C8H14O4
• M. W.: 174.19436
• Purity: ≥99.0% (sum of enantiomers, GC)

SYNONYMS

• Title: (R)-1-乙基氢-3-甲基戊二酸酯
• IUPAC name: (3R)-5-ethoxy-3-methyl-5-oxopentanoic acid
• IUPAC Traditional name: (3R)-5-ethoxy-3-methyl-5-oxopentanoic acid
• Synonyms: 3-甲基戊二酸-(R)-单乙酯; (R)-mono-Ethyl 3-methylglutarate; (R)-Monoethyl 3-methylglutarate

DATABASE IDS

• PubChem SID: 24885064
• MDL Number: MFCD00077820
• CAS Number: 72594-19-5
• Beilstein Number: 1562576

PROPERTIES

• Empirical Formula (Hill Notation): C8H14O4
• Optical Purity: enantiomeric ratio: ~98:2 (GC)
• Purity: ≥99.0% (sum of enantiomers, GC)
• Boiling Point: 74-76 °C/0.03 mmHg(lit.)
• Density: 1.076 g/mL at 20 °C(lit.)
• Optical Rotation: [α]20/D -1.3±0.2°, neat
• Refractive Index: n20/D 1.437
• Personal Protective Equipment: Eyeshields, Gloves
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Enantiomerically pure monoesters of 3-methylglutarate allow the preparation of important chiral building blocks: synthesis of both enantiomers of β-methyl-γ-valerolactone1; synthesis of (R)-3-methylhexanol2; Kolbe synthesis of long-chain acids3; preparation of a verrucarinic building block4
Packaging
1 mL in glass bottle

Description (简体中文)

Other Notes
3-甲基戊二酸的对映纯单酯可用于制备重要的手性结构单元：合成 β-甲基-γ-戊内酯的两种对映体1；合成 (R)-3-甲基己醇2；Kolbe 法合成长链酸3；制备疣孢菌素结构单元4
包装
1 mL in glass bottle