N,N-Diethyl-1,1,2,3,3,3-hexafluoropropylamine

• Catalog No.: 564990
• CAS Number: 309-88-6
• M. F.: C7H11F6N
• M. W.: 223.1593592

SYNONYMS

• Title: N,N-二乙基-1,1,2,3,3,3-六氟丙胺
• IUPAC name: diethyl(1,1,2,3,3,3-hexafluoropropyl)amine
• IUPAC Traditional name: diethyl(1,1,2,3,3,3-hexafluoropropyl)amine
• Synonyms: Ishikawa’s Reagent; Ishikawa 试剂

DATABASE IDS

• PubChem SID: 24880211
• MDL Number: MFCD00054683
• CAS Number: 309-88-6

PROPERTIES

• Linear Formula: CF3CHFCF2N(C2H5)2
• Boiling Point: 56-57 °C(lit.)
• Density: 1.230 g/mL at 25 °C(lit.)
• Flash Point: 40 °C
• Flash Point: 104 °F
• Refractive Index: n20/D 1.3460(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H226-H314
• European Hazard Symbols: Corrosive (C)
• Personal Protective Equipment: Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US)
• GHS Precautionary statements: P280-P305 + P351 + P338-P310
• RID/ADR: UN 2920 8/PG 2
• Risk Statements: 10-34
• Safety Statements: 16-26-36/37/39-45
• Hazard Class: 8
• UN Number: 2920
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Application
Demonstrates utility in fluorination.7
Displays the ability to insert a fluoro(trifluoromethyl) methylene moiety in unsaturated alcohols.
Reactant for:
• Friedel-Crafts type arylation of hydrofluorocarbons1
• Microbial hydroxylation of antibiotics2
• Electrochemical fluorination of trialkylamines and tetraalkylammonium salts3
• Fluorination of pyrethroides4Reactant for synthesis of:
• γ-Hydroxy-α-fluoro-α-trifluoromethylcarboxamide5
• Florfenicol and thiamphenicol6
Packaging
25 g in glass bottle
General description
GC analysis includes Et2NCF=CFCF3 (two isomers), both of which are active fluorinating agents.

Description (简体中文)

Application
可用于氟化反应。7
能够在不饱和醇中插入氟代(三氟甲基)亚甲基部分。
Reactant for:
• Friedel-Crafts type arylation of hydrofluorocarbons1
• Microbial hydroxylation of antibiotics2
• Electrochemical fluorination of trialkylamines and tetraalkylammonium salts3
• Fluorination of pyrethroides4Reactant for synthesis of:
• γ-Hydroxy-α-fluoro-α-trifluoromethylcarboxamide5
• Florfenicol and thiamphenicol6
包装
25 g in glass bottle
General description
GC analysis includes Et2NCF=CFCF3 (two isomers), both of which are active fluorinating agents.