L-Ethionine

• Catalog No.: 219339
• CAS Number: 13073-35-3
• M. F.: C6H13NO2S
• M. W.: 163.23792
• Purity: 98%

SYNONYMS

• Title: L-乙硫氨基酪酸
• IUPAC name: (2S)-2-amino-4-(ethylsulfanyl)butanoic acid
• IUPAC Traditional name: (.+-.)-ethionine
• Synonyms: L-2-氨基-4-(乙硫基)丁酸; L-2-Amino-4-(ethylthio)butyric acid

DATABASE IDS

• CAS Number: 13073-35-3
• MDL Number: MFCD00002626
• EC Number: 235-966-4

PROPERTIES

• Linear Formula: C2H5SCH2CH2CH(NH2)CO2H
• Purity: 98%
• Melting Point: 280 °C (dec.)(lit.)
• Optical Rotation: [α]22/D +21.7°, c = 1 in 1 M HCl
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: ES6825300
• Safety Statements: 26
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
An analog of methionine that interferes with the normal methylation of DNA and other methylation pathways, and induces pancreatic toxicity and liver cancer. However, in animal studies, it has also been shown to act synergistically with methionine-depletion to block the growth and metastasis of methionine-dependent tumors.
Packaging
5 g in glass bottle

Description (简体中文)

Biochem/physiol Actions
甲硫氨酸类似物，会干扰 DNA 的标准甲基化和其他甲基化途径，从而导致胰腺中毒和肝癌。但在动物研究中，也显示出与甲硫氨酸消耗的同步活动，以阻止甲硫氨酸依赖性肿瘤的生长和转移。
包装
5 g in glass bottle