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Triamcinolone

Catalog No. 287334 Name Sigma Aldrich
CAS Number 124-94-7 Website http://www.sigmaaldrich.com
M. F. C21H27FO6 Telephone 1-800-521-8956
M. W. 394.4338832 Fax
Purity Email
Storage Chembase ID: 502

SYNONYMS

IUPAC name
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
IUPAC Traditional name
triamcinolone
Synonyms
9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-Fluoro-11β,16α,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
Fluoxyprednisolone

DATABASE IDS

MDL Number MFCD00010477
EC Number 204-718-7
PubChem SID 24857272
CAS Number 124-94-7

PROPERTIES

Empirical Formula (Hill Notation) C21H27FO6
Melting Point 262-263 °C(lit.)
Optical Rotation [α]25/D +69°, c = 2 in DMF
GHS Pictograms GHS08
GHS Signal Word Warning
GHS Hazard statements H351
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P281
Risk Statements 40
RTECS TU3850000
Safety Statements 22-36
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Triamcinolone is a synthetic glucocorticoid agonist; induces gene expression and apoptosis; inhibits prostaglandin synthesis; impairs tumor necrosis factor (TNF)-α-induced degradation of κB-α; potentiates the differentiation-inducing effects of bone morphogenetic proteins (BMP-2, -4, -6).
Packaging
1 g in glass bottle
250 mg in glass bottle
Description (简体中文)
Biochem/physiol Actions
Triamcinolone is a synthetic glucocorticoid agonist; induces gene expression and apoptosis; inhibits prostaglandin synthesis; impairs tumor necrosis factor (TNF)-α-induced degradation of κB-α; potentiates the differentiation-inducing effects of bone morphogenetic proteins (BMP-2, -4, -6).
包装
1 g in glass bottle
250 mg in glass bottle

REFERENCES