Benzyl chloroformate

• Catalog No.: 119938
• CAS Number: 501-53-1
• M. F.: C8H7ClO2
• M. W.: 170.59298
• Purity: 95%

SYNONYMS

• Title: 氯甲酸苄酯
• IUPAC name: benzyl chloroformate
• IUPAC Traditional name: benzyl chloroformate
• Synonyms: 苯甲氧羰酰氯; 苯甲氧基甲酰氯; Z-Chloride; Carbobenzoxy chloride

DATABASE IDS

• MDL Number: MFCD00000640
• PubChem SID: 24847303
• CAS Number: 501-53-1
• Beilstein Number: 509751

PROPERTIES

• Grade: technical grade
• Linear Formula: ClCO2CH2C6H5
• Purity: 95%
• Boiling Point: 103 °C/20 mmHg(lit.)
• Density: 1.195 g/mL at 25 °C(lit.)
• Flash Point: 92 °C
• Flash Point: 197.6 °F
• Refractive Index: n20/D 1.519(lit.)
• Vapor Density: 1 (vs air)
• Vapor Pressure: 1.39 psi ( 20 °C)
• GHS Signal Word: Danger
• GHS Hazard statements: H314-H335-H350-H410
• European Hazard Symbols: Toxic (T)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P201-P261-P273-P280-P305 + P351 + P338-P310
• RID/ADR: UN 1739 8/PG 1
• Risk Statements: 45-34-37-50/53
• Safety Statements: 53-26-36/37/39-45-61
• Storage Temperature: 2-8°C
• Hazard Class: 8
• UN Number: 1739
• Packing Group: 1
• German water hazard class: 3

DETAILS

Description (English)

Application
Cbz-protected anilines were prepared directly from aromatic carboxylic acids, sodium azide and Cbz-Cl.1 Also used in a recently reported 3-step synthesis of 1,2,4-oxadiazoles.2
Protecting reagent in peptide synthesis.
Useful for the introduction of the benzyloxycarbonyl(Cbz,Z) protecting group
Packaging
100 g in Sure/Seal™
2.5 kg in Sure/Seal™
5 g in glass bottle

Description (简体中文)

Application
用于引入苄氧羰基 (Cbz,Z) 保护基团
用于肽合成的保护剂。
苄氧羰基保护的苯胺可直接用芳香羧酸、叠氮化钠和苯甲氧羰酰氯制备。1还可用于最近报道的 1,2,4-噁二唑的三步合成反应。2
包装
100 g in Sure/Seal™
2.5 kg in Sure/Seal™
5 g in glass bottle