2-(Trimethylsilyl)ethoxymethyl chloride

• Catalog No.: 238902
• CAS Number: 76513-69-4
• M. F.: C6H15ClOSi
• M. W.: 166.7212

SYNONYMS

• Title: 2-(三甲基硅烷基)乙氧甲基氯
• IUPAC name: [2-(chloromethoxy)ethyl]trimethylsilane
• IUPAC Traditional name: [2-(chloromethoxy)ethyl]trimethylsilane
• Synonyms: (2-氯甲氧基乙基)三甲基硅烷; Chloromethyl 2-trimethylsilylethyl ether; SEM-chloride; (2-Chloromethoxyethyl)trimethylsilane; SEM-Cl; SEM-氯化物; 氯甲基三甲基硅乙基醚

DATABASE IDS

• EC Number: 278-483-4
• MDL Number: MFCD00009919
• PubChem SID: 24854351
• CAS Number: 76513-69-4
• Beilstein Number: 3587289

PROPERTIES

• Contains: 10 ppm diisopropylethylamine as stabilizer
• Grade: technical grade
• Linear Formula: (CH3)3SiCH2CH2OCH2Cl
• Boiling Point: 170-172 °C(lit.)
• Boiling Point: 57-59 °C/8 mmHg(lit.)
• Density: 0.942 g/mL at 25 °C(lit.)
• Flash Point: 46 °C
• Flash Point: 114.8 °F
• Refractive Index: n20/D 1.435(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H226-H314
• European Hazard Symbols: Corrosive (C)
• Personal Protective Equipment: Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P280-P305 + P351 + P338-P310
• RID/ADR: UN 2920 8/PG 2
• Risk Statements: 10-34
• Safety Statements: 26-28-36/37/39-45
• Storage Temperature: 2-8°C
• Hazard Class: 8
• UN Number: 2920
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Phenol protecting group in the synthesis of laterifluorones.1
Used to prepare a SEM-ether which was, in turn, removed with BBr3 and cyclized to a benzo-oxapane.
Features and Benefits
Convenient hydroxyl-protecting reagent. SEM-ethers are stable over a wide pH range, and can be selectively cleaved with fluoride ion under mild aprotic conditions.2,3
Packaging
1, 5, 25, 100 g in glass bottle

Description (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
在 laterifluorone 的合成中作为苯酚保护基团。1
用于制备 SEM-醚，SEM-醚又可被 BBr3 除去，并且发生环化反应生成 benzo-oxapane。
Features and Benefits
方便的羟基保护试剂。SEM-醚可在很宽的 pH 范围内稳定存在，在温和非质子条件下可被氟离子选择性裂解。2,3
包装
1, 5, 25, 100 g in glass bottle