tert-Butyl diethylphosphonoacetate

• Catalog No.: 348333
• CAS Number: 27784-76-5
• M. F.: C10H21O5P
• M. W.: 252.244501
• Purity: 95%

SYNONYMS

• Title: 二乙基膦酰基乙酸叔丁酯
• IUPAC name: tert-butyl 2-(diethoxyphosphoryl)acetate
• IUPAC Traditional name: tert-butyl 2-(diethoxyphosphoryl)acetate
• Synonyms: tert-Butyl (diethoxyphosphinyl)acetate; (Diethoxyphosphinyl)acetic acid 1,1-dimethylethyl ester; Diethyl tert-butoxycarbonylmethanephosphonate

DATABASE IDS

• CAS Number: 27784-76-5
• PubChem SID: 24861567
• MDL Number: MFCD00075414

PROPERTIES

• Linear Formula: (C2H5O)2P(O)CH2CO2C(CH3)3
• Purity: 95%
• Boiling Point: 100-103 °C/1.5 mmHg(lit.)
• Density: 1.074 g/mL at 25 °C(lit.)
• Flash Point: >113 °C
• Flash Point: >235.4 °F
• Refractive Index: n20/D 1.431(lit.)
• Personal Protective Equipment: Eyeshields, Gloves
• German water hazard class: 3

DETAILS

Description (English)

Packaging
5 g in glass bottle
Application
Reactant for:
• Preparation of ydroxymethylated dihydroxyvitamin D3 analogs via Wittig-Horner approach, as potential antitumor agents1
• Synthesis of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat 3)2
• One-pot synthesis of the DPP4-selective inhibitor ABT-341 by a four-component coupling mediated by a diphenylprolinol silyl ether3
• Bicyclic triaminophosphine-promoted stereoselective synthesis of a,β-unsaturated esters, fluorides, and nitriles from aldehydes and ketones using Wadsworth-Emmons phosphonates4
• Preparation of amidopropenyl hydroxamates as human histone deacetylase (HDAC) inhibitors5

Description (简体中文)

包装
5 g in glass bottle
Application
Reactant for:
• Preparation of ydroxymethylated dihydroxyvitamin D3 analogs via Wittig-Horner approach, as potential antitumor agents1
• Synthesis of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat 3)2
• One-pot synthesis of the DPP4-selective inhibitor ABT-341 by a four-component coupling mediated by a diphenylprolinol silyl ether3
• Bicyclic triaminophosphine-promoted stereoselective synthesis of a,β-unsaturated esters, fluorides, and nitriles from aldehydes and ketones using Wadsworth-Emmons phosphonates4
• Preparation of amidopropenyl hydroxamates as human histone deacetylase (HDAC) inhibitors5