(S)-(+)-Epichlorohydrin

• Catalog No.: 540080
• CAS Number: 67843-74-7
• M. F.: C3H5ClO
• M. W.: 92.5242
• Purity: 98%

SYNONYMS

• Title: (S)-(+)-环氧氯丙烷
• IUPAC name: (2S)-2-(chloromethyl)oxirane
• IUPAC Traditional name: (S)-epichlorohydrin
• Synonyms: (S)-(+)-2-(氯甲基)环氧乙烷; (S)-(+)-2-(Chloromethyl)oxirane

DATABASE IDS

• CAS Number: 67843-74-7
• PubChem SID: 24878439
• Beilstein Number: 1420784
• MDL Number: MFCD00077760

PROPERTIES

• Empirical Formula (Hill Notation): C3H5ClO
• Optical Purity: ee: 97% (GLC)
• Purity: 98%
• Auto Ignition Point: 1421 °F
• Boiling Point: 92-93 °C/360 mmHg(lit.)
• Density: 1.183 g/mL at 25 °C(lit.)
• Flash Point: 32 °C
• Flash Point: 89.6 °F
• Optical Rotation: [α]20/D +35°, c = 1 in methanol
• Refractive Index: n20/D 1.438(lit.)
• Vapor Density: 3.2 (vs air)
• Vapor Pressure: 12.5 mmHg ( 20 °C)
• Explode Limits: 21 %
• GHS Signal Word: Danger
• GHS Hazard statements: H226-H301-H311-H314-H317-H331-H350
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P201-P261-P280-P301 + P310-P305 + P351 + P338-P310
• RID/ADR: UN 2023 6.1/PG 2
• Risk Statements: 45-10-23/24/25-34-43
• RTECS: RR0427100
• Safety Statements: 53-45
• Hazard Class: 6.1
• UN Number: 2023
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Application
Chiral building block in the enantioselective syntheses of hydroxyisoxazolidines1 and (+)-cis-sylvaticin, a potential antitumor agent.2
Used in the total synthesis of Macquarimicins and in the total synthesis of the macrolide RK-397.
Used to synthesize inhibitors of fatty acid oxidation as potential metabolic modulators.
Packaging
5, 25 g in glass bottle
Legal Information
Manufactured under license by Shasun Chemicals and Drugs Limited, using Jacobsen HKR technology.

Description (简体中文)

Application
作为潜在的代谢调节剂，用以合成脂肪酸氧化抑制剂。
用于 Macquarimicins 的全合成和大环内酯 RK-397 的全合成。
用于对映选择性合成羟基异噁唑烷1和 (+)-顺式-sylvaticin（一种有潜力的抗肿瘤剂）的手性结构单元。2
包装
5, 25 g in glass bottle
Legal Information
经 Shasun Chemicals and Drugs Limited 授权，使用 Jacobsen HKR 技术制造。