[Bis(trifluoroacetoxy)iodo]benzene

• Catalog No.: 232130
• CAS Number: 2712-78-9
• M. F.: C10H5F6IO4
• M. W.: 430.0391892
• Purity: 97%

SYNONYMS

• Title: [双(三氟乙酰氧基)碘]苯
• IUPAC name: phenyl[(trifluoroacetyl)oxy]-λ^3-iodanyl 2,2,2-trifluoroacetate
• IUPAC Traditional name: phenyl[(trifluoroacetyl)oxy]-λ^3-iodanyl 2,2,2-trifluoroacetate
• Synonyms: Iodobenzene I,I-bis(trifluoroacetate); PIFA; BTI; I,I-双(三氟乙酸)碘苯

DATABASE IDS

• CAS Number: 2712-78-9
• EC Number: 220-308-0
• MDL Number: MFCD00009672
• PubChem SID: 24853882
• Beilstein Number: 764767

PROPERTIES

• Linear Formula: (CF3CO2)2IC6H5
• Purity: 97%
• Melting Point: 121-125 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Packaging
10, 50 g in glass bottle
Application
Reactant or reagent for:
• Pummerer-like reactions1,2
• Chemoselective deprotection of dimethoxybenzyl ethers3
• Mediating oxidative cycloisomerization4,5
• Tosyloxylation of anilides6
Used for the direct α-hydroxylation of ketones under acidic conditions. Also employed as a p-fluorination reagent of 4-alkylphenols in the presence of HF·pyridine (cat. no. 184225) for synthesis of 4-fluorocyclohexa-2,5-dienones.Reagent for the oxidation of N-acylhydrazones to 1,3,4-oxadiazoles. Promotes the cyclization of styryl amines to N-alkyl or N-aryl indoles.

Description (简体中文)

包装
10, 50 g in glass bottle
Application
Reactant or reagent for:
• Pummerer-like reactions1,2
• Chemoselective deprotection of dimethoxybenzyl ethers3
• Mediating oxidative cycloisomerization4,5
• Tosyloxylation of anilides6
在酸性条件下用于酮的直接 α-羟基化反应。也可作为 4-烷基酚的对氟化试剂，可在吡啶氢氟酸盐（产品目录号184225）存在的条件下合成 4-氟环己-2,5-二烯酮。 用于 N-酰腙经氧化反应生成 1,3,4-噁二唑的试剂。促进苯乙烯胺环化反应生成 N-烷基吲哚或 N-芳基吲哚。