Diethyl (bromodifluoromethyl)phosphonate

• Catalog No.: 411361
• CAS Number: 65094-22-6
• M. F.: C5H10BrF2O3P
• M. W.: 267.0056674
• Purity: 96%

SYNONYMS

• Title: 溴氟甲基膦酸二乙酯
• IUPAC name: diethyl (bromodifluoromethyl)phosphonate
• IUPAC Traditional name: diethyl bromodifluoromethylphosphonate
• Synonyms: (Bromodifluoromethyl)phosphonic acid diethyl ester

DATABASE IDS

• PubChem SID: 24865745
• MDL Number: MFCD00069118
• CAS Number: 65094-22-6

PROPERTIES

• Linear Formula: BrCF2P(O)(OC2H5)2
• Purity: 96%
• Boiling Point: 40-41 °C/0.05 mmHg(lit.)
• Density: 1.503 g/mL at 25 °C(lit.)
• Flash Point: >113 °C
• Flash Point: >235.4 °F
• Refractive Index: n20/D 1.417(lit.)
• Personal Protective Equipment: Eyeshields, Gloves
• German water hazard class: 3

DETAILS

Description (English)

Packaging
5 g in glass bottle
Application
Reactant for:
• Preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3)1
• Synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps2
• P-C bond cleavage on basic hydrolysis3
• Preparation of a prodrug for intracellular delivery of protein tyrosine phosphatase 1B (PTP1B) inhibitor (nonhydrolyzable difluoromethylphosphonate moiety)4

Description (简体中文)

包装
5 g in glass bottle
Application
Reactant for:
• Preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3)1
• Synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps2
• P-C bond cleavage on basic hydrolysis3
• Preparation of a prodrug for intracellular delivery of protein tyrosine phosphatase 1B (PTP1B) inhibitor (nonhydrolyzable difluoromethylphosphonate moiety)4