(R)-(-)-Epichlorohydrin

• Catalog No.: 540072
• CAS Number: 51594-55-9
• M. F.: C3H5ClO
• M. W.: 92.5242
• Purity: 99%

SYNONYMS

• Title: (R)-(-)-环氧氯丙烷
• IUPAC name: (2R)-2-(chloromethyl)oxirane
• IUPAC Traditional name: (-)-epichlorohydrin
• Synonyms: (R)-(-)-2-(氯甲基)环氧乙烷; (R)-(-)-2-(Chloromethyl)oxirane

DATABASE IDS

• EC Number: 424-280-2
• Beilstein Number: 1420785
• CAS Number: 51594-55-9
• MDL Number: MFCD00077759
• PubChem SID: 24878437

PROPERTIES

• Empirical Formula (Hill Notation): C3H5ClO
• Optical Purity: ee: 98% (GLC)
• Purity: 99%
• Auto Ignition Point: 772 °F
• Boiling Point: 114 °C(lit.)
• Density: 1.180 g/mL at 20 °C(lit.)
• Flash Point: 32 °C
• Flash Point: 89.6 °F
• Optical Rotation: [α]20/D -34°, c = 1 in methanol
• Refractive Index: n20/D 1.438(lit.)
• Vapor Density: 3.29 (vs air)
• Vapor Pressure: 10 mmHg ( 16.6 °C)
• Explode Limits: 21 %
• GHS Signal Word: Danger
• GHS Hazard statements: H226-H301-H311-H314-H317-H331-H350
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P201-P261-P280-P301 + P310-P305 + P351 + P338-P310
• RID/ADR: UN 2023 6.1/PG 2
• Risk Statements: 45-10-23/24/25-34-43
• RTECS: RR0427000
• Safety Statements: 53-45
• Hazard Class: 6.1
• UN Number: 2023
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Application
Building block for the synthesis of a key intermediate in the synthesis of stable PGI2 analogue UT-15.1
Used in the synthesis of chiral morpholines and dioxanes via a Mitsunobu diol-cyclization. Chiral building block in the enantioselective synthesis of trans-2,4-disubstituted piperidines.
Packaging
5, 25 g in glass bottle
Legal Information
Manufactured under license by Shasun Chemicals and Drugs Limited, using Jacobsen HKR technology.

Description (简体中文)

Application
用于稳定 PGI2 类似物 UT-151 合成的重要中间体合成的结构单元。
用于通过 Mitsunobu 二醇环化作用合成手性吗啉和二噁烷。用作反式-2,4-二取代哌啶的对映选择性合成的手性结构单元。
包装
5, 25 g in glass bottle
Legal Information
经 Shasun Chemicals and Drugs Limited 授权，使用 Jacobsen HKR 技术制造。