(S)-(-)-2-Methyl-2-propanesulfinamide

• Catalog No.: 513210
• CAS Number: 343338-28-3
• M. F.: C4H11NOS
• M. W.: 121.20124
• Purity: 97%

SYNONYMS

• Title: (S)-(-)-2-甲基-2-丙烷亚磺酰胺
• IUPAC name: (S)-2-methylpropane-2-sulfinamide
• IUPAC Traditional name: (S)-2-methylpropane-2-sulfinamide

DATABASE IDS

• PubChem SID: 24873681
• MDL Number: MFCD05861480
• CAS Number: 343338-28-3

PROPERTIES

• Linear Formula: (CH3)3CS(O)NH2
• Purity: 97%
• Melting Point: 97-101 °C(lit.)
• Optical Rotation: [α]20/D -4.5°, c = 1 in chloroform
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Can be readily transformed into P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins.1
Chiral auxiliary used in an asymmetric preparation of trifluoroethylamines by conversion of trifluoroacetaldehyde to a chiral imine followed by treatment with an aryl lithium and acidic methanolysis.
Useful reagent for synthesizing chiral amines.
Ellman′s Sulfinamides
Packaging
1, 5, 25 g in glass bottle

Description (简体中文)

Application
不对称制备三氟乙胺的手性助剂，反应先将三氟乙醛转化为手性亚胺，然后进行芳基锂处理和酸性甲醇分解。
合成手性胺的有效试剂。
易与醛和酮发生缩合反应，转化为 P,N-亚磺酰亚胺配体，该配体可参与烯烃的铱催化不对称氢化反应。1
Ellman′s Sulfinamides
包装
1, 5, 25 g in glass bottle