Diisopropyl azodicarboxylate

• Catalog No.: 225541
• CAS Number: 2446-83-5
• M. F.: C8H14N2O4
• M. W.: 202.20776
• Purity: 98%

SYNONYMS

• Title: 偶氮二甲酸二异丙酯
• IUPAC name: N-{[(propan-2-yloxy)carbonyl]imino}(propan-2-yloxy)formamide
• IUPAC Traditional name: diisopropyl azodicarboxylate
• Synonyms: Diisopropyl azodiformate; DIAD

DATABASE IDS

• MDL Number: MFCD00008875
• PubChem SID: 24853505
• Beilstein Number: 1912326
• CAS Number: 2446-83-5

PROPERTIES

• Impurities: ≤2% dichloromethane
• Linear Formula: (CH3)2CHOOCN=NCOOCH(CH3)2
• Purity: 98%
• Boiling Point: 75 °C/0.25 mmHg(lit.)
• Density: 1.027 g/mL at 25 °C(lit.)
• Flash Point: 106 °C
• Flash Point: 222.8 °F
• Refractive Index: n20/D 1.420(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335-H351-H373-H411
• European Hazard Symbols: Harmful (Xn)
• European Hazard Symbols: Nature polluting (N)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P261-P273-P281-P305 + P351 + P338
• RID/ADR: UN 3082 9/PG 3
• Risk Statements: 36/37/38-40-48/20/22-51/53
• Safety Statements: 26-36/37-61
• Storage Temperature: 2-8°C
• Hazard Class: 9
• UN Number: 3082
• Packing Group: 3
• German water hazard class: 2

DETAILS

Description (English)

General description
Reacted with dioxaphosphorinanes and iron catalyst to generate rearranged phosphonium ylide products.8
Packaging
25, 100 g in poly bottle
5 g in glass bottle
Application
Reactant for preparation of:
• Chromenes resembling classical cannabinoids1
• MK-3281 inhibitor of the hepatitis C virus NS5B polymerase2
• Norbornene-based guanidine-rich polymers as mimcs of cell-penetrating peptides (CPP)3
• Analogues of the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-l-homoserine lactone with immunosuppressive but non-LasR-inducing properties4
• Acceptor-donor-acceptor organic dyes for dye-sensitized solar cells5
• 1,3-dioxane-2-carboxylic acid derivatives as PPARα/γ dual agonists6
• Hydrazinophosphonates and hydrazinobisphosphonates via Mitsunobu and Arbuzov-type multicomponent application of the Morrison-Brunn-Huisgen betaine7

Description (简体中文)

General description
在铁催化剂催化下与二氧磷杂环己烷反应生成重排膦叶立德产物。8
包装
25, 100 g in poly bottle
5 g in glass bottle
Application
Reactant for preparation of:
• Chromenes resembling classical cannabinoids1
• MK-3281 inhibitor of the hepatitis C virus NS5B polymerase2
• Norbornene-based guanidine-rich polymers as mimcs of cell-penetrating peptides (CPP)3
• Analogues of the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-l-homoserine lactone with immunosuppressive but non-LasR-inducing properties4
• Acceptor-donor-acceptor organic dyes for dye-sensitized solar cells5
• 1,3-dioxane-2-carboxylic acid derivatives as PPARα/γ dual agonists6
• Hydrazinophosphonates and hydrazinobisphosphonates via Mitsunobu and Arbuzov-type multicomponent application of the Morrison-Brunn-Huisgen betaine7