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trans-4-Hydroxy-L-proline

Catalog No. H54409 Name Sigma Aldrich
CAS Number 51-35-4 Website http://www.sigmaaldrich.com
M. F. C5H9NO3 Telephone 1-800-521-8956
M. W. 131.12986 Fax
Purity ≥99% Email
Storage Chembase ID: 91182

SYNONYMS

Title
L-羟基脯氨酸
IUPAC name
(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
IUPAC Traditional name
hypro
Synonyms
(2S,4R)-4-羟基吡咯烷-2-羧酸
Hyp
(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid

DATABASE IDS

CAS Number 51-35-4
PubChem SID 24895692
EC Number 200-091-9
Beilstein Number 81441
MDL Number MFCD00064320

PROPERTIES

Empirical Formula (Hill Notation) C5H9NO3
Purity ≥99%
Melting Point 273 °C (dec.)(lit.)
Optical Rotation [α]25/D -75.6°, c = 1 in H2O
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class 3

DETAILS

Description (English)
Other Notes
Natural constituent of animal structural proteins such as collagen and elastin.
Packaging
10, 25, 100 g in poly bottle
2.5 g in glass bottle
Application
Versatile reagent for the synthesis of neuroexcitatory kainoids1 and antifungal echinocandins.2 Also employed in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.3
Description (简体中文)
Other Notes
动物结构蛋白(如胶原和弹性蛋白)的天然成分。
包装
10, 25, 100 g in poly bottle
2.5 g in glass bottle
Application
合成神经兴奋 kainoid 1和抗真菌棘白菌素的多功能试剂。2也可用于合成手性配体,该配体可用于醛的不对称乙基化。3

REFERENCES