(S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminomanganese(III) chloride

• Catalog No.: 404454
• CAS Number: 135620-04-1
• M. F.: C36H52ClMnN2O2
• M. W.: 635.201329

SYNONYMS

• Title: (S,S)-(+)-N,N′-双(3,5-二-叔丁基亚水杨基)-1,2-环己二胺氯化锰(III)
• IUPAC name: (4S,9S)-14,16,22,24-tetra-tert-butyl-19-chloro-18,20-dioxa-3,10-diaza-19-manganatetracyclo[19.4.0.0^4,^9.0^1^2,^1^7]pentacosa-1(21),2,10,12,14,16,22,24-octaene
• IUPAC Traditional name: (4S,9S)-14,16,22,24-tetra-tert-butyl-19-chloro-18,20-dioxa-3,10-diaza-19-manganatetracyclo[19.4.0.0^4,^9.0^1^2,^1^7]pentacosa-1(21),2,10,12,14,16,22,24-octaene
• Synonyms: (S,S)-Jacobsen’s catalyst; (S,S)-Jacobsen 催化剂

DATABASE IDS

• MDL Number: MFCD02101663
• CAS Number: 135620-04-1
• PubChem SID: 24865247

PROPERTIES

• Linear Formula: [[[(CH3)3C]2C6H2-2-(O-)CH=N]2C6H10]MnCl
• Melting Point: 330-332 °C(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Application
Salen (Mn)-catalyzed asymmetric epoxidation of unfunctionalized olefins.6,7,8,9 High enantioselectivities and yields are obtained for a variety of substrates,6 especially cis-alkenes. A few applications include the synthesis of the taxol side chain10 and cis-1-amino-2-indanol.11,12 Jacobsen′s catalyst has also been used in the asymmetric α-hydroxylation of silyl enol ethers.13 Catalyst for the enantioselective epoxidation of a variety of olefins.13,14
Reactant involved in:
• Studies of intercalative binding with ct-DNA and radical scavenging antioxidant activity1
• Immobilization on phenoxy-modified zirconium poly(styrenephenylvinylphosphonate)2
• Synthesis of derivatvies for studies of conformational models of enantioselective reactions3Catalyst involved in:
• Asymmetric epoxidation of olefins4
• Immobilization on ionic liquid modified mesoporous silica for oxidative kinetic resolution of racemic secondary alcohols†
• Immobilization on diamine modified zirconium olig-styrenyl phosphonate hydrogen phosphate for epoxidation of styrene5
Packaging
1, 5, 25 g in glass bottle
Legal Information
Manufactured under license by Shasun Chemicals and Drugs Limited, using Jacobsen HKR technology.

Description (简体中文)

Application
非官能化烯烃类的 Salen (Mn)-催化不对称环氧化反应。6,7,8,9获得各种底物6（特别是顺式-烯烃）的高对映立体选择性和产量。一些用途包括合成紫杉醇侧链10和顺式-1-氨基-2-茚醇。11,12Jacobsen 催化剂还用于硅烯醇醚的不对称 α-羟基化。13用于各种烯烃不对称环氧化反应的催化剂。13,14
Reactant involved in:
• Studies of intercalative binding with ct-DNA and radical scavenging antioxidant activity1
• Immobilization on phenoxy-modified zirconium poly(styrenephenylvinylphosphonate)2
• Synthesis of derivatvies for studies of conformational models of enantioselective reactions3Catalyst involved in:
• Asymmetric epoxidation of olefins4
• Immobilization on ionic liquid modified mesoporous silica for oxidative kinetic resolution of racemic secondary alcohols†
• Immobilization on diamine modified zirconium olig-styrenyl phosphonate hydrogen phosphate for epoxidation of styrene5
包装
1, 5, 25 g in glass bottle
Legal Information
经 Shasun Chemicals and Drugs Limited 授权，使用 Jacobsen HKR 技术制造。