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1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate_Molecular_structure_CAS_148893-10-1)
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1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate

Catalog No. 445460 Name Sigma Aldrich
CAS Number 148893-10-1 Website http://www.sigmaaldrich.com
M. F. C10H15F6N6OP Telephone 1-800-521-8956
M. W. 380.2298802 Fax
Purity 97% Email
Storage Chembase ID: 100325

SYNONYMS

IUPAC name
[(dimethylamino)({3H-[1,2,3]triazolo[4,5-b]pyridin-3-yloxy})methylidene]dimethylazanium; hexafluoro-λ5-phosphanuide
IUPAC Traditional name
[(dimethylamino)({[1,2,3]triazolo[4,5-b]pyridin-3-yloxy})methylidene]dimethylazanium hexafluorophosphate
Synonyms
HATU
N,N,N′,N′-四甲基-O-(7-氮杂苯并三唑-1-基)六氟磷酸脲
N-[(Dimethylamino)-1H-1,2,3-triazolo-[4,5-b]pyridin-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide

DATABASE IDS

CAS Number 148893-10-1
PubChem SID 24868183

PROPERTIES

Empirical Formula (Hill Notation) C10H15F6N6OP
Purity 97%
Melting Point 183-185 °C(lit.)
GHS Pictograms GHS02
GHS Pictograms GHS07
GHS Signal Word Danger
GHS Hazard statements H228-H315-H319-H335
European Hazard Symbols Explosive Explosive (E)
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P210-P261-P305 + P351 + P338
Risk Statements 2-36/37/38
Safety Statements 26-35
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Application
Peptide coupling reagent.
Preparation of N-arylsulfonamide-linked peptides by solid-phase synthesis.1
Reagent for: Synthesis of Aurora A kinase inhibitors1 HPLC assay to determine D- and L- acid enantiomers in human plasma2 Amide bond formation reactions3Catalyst for: Selective acylation4 Selecocyclization-oxidation deselenation sequence5
Packaging
1, 5 g in glass bottle
25 g in poly bottle
Description (简体中文)
Application
肽偶联剂。
通过固相合成制备 N-芳基磺酰胺键合肽。1
Reagent for: Synthesis of Aurora A kinase inhibitors1 HPLC assay to determine D- and L- acid enantiomers in human plasma2 Amide bond formation reactions3Catalyst for: Selective acylation4 Selecocyclization-oxidation deselenation sequence5
包装
1, 5 g in glass bottle
25 g in poly bottle

REFERENCES