Andrographolide

• Catalog No.: 365645
• CAS Number: 5508-58-7
• M. F.: C20H30O5
• M. W.: 350.4492
• Purity: 98%

SYNONYMS

• Title: 穿心莲内酯
• IUPAC name: (4S)-3-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-decahydronaphthalen-1-yl]ethylidene}-4-hydroxyoxolan-2-one
• IUPAC Traditional name: (4S)-3-{2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-hexahydro-1H-naphthalen-1-yl]ethylidene}-4-hydroxyoxolan-2-one

DATABASE IDS

• Beilstein Number: 42762
• PubChem SID: 24862550
• CAS Number: 5508-58-7
• EC Number: 226-852-5
• MDL Number: MFCD07778082

PROPERTIES

• Empirical Formula (Hill Notation): C20H30O5
• Purity: 98%
• Melting Point: 229-232 °C(lit.)
• Optical Rotation: [α]20/D -126°, c = 1.5 in acetic acid
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: LU3490750
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Diterpenoid lactone with anti-inflammatory properties. It blocks T-cell proliferation to allogenic stimuli and the chemotactic migration of macrophages induced by complement. Blocks the proliferation of several cancer cell lines in vitro.
Packaging
100, 500 mg in glass bottle

Description (简体中文)

Biochem/physiol Actions
具有抗炎特性的双萜内酯。它可阻断外源刺激下的 T 细胞增殖和补体诱导的巨噬细胞趋化迁移。可阻断几种癌细胞系的体外增殖。
包装
100, 500 mg in glass bottle